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Structural biology: A picornavirus unlike the others

Technological breakthroughs in cryo-electron microscopy are allowing the capture of virus structures, leading to advances in the field of viral microbiology almost daily. An innovative structure–function study on Aichi virus reveals that novel entry mechanisms, yet undiscovered, may exist for non-enveloped viruses.

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Figure 1: Picornavirus genome release.

References

  1. Fendrick, A. M., Monto, A. S., Nightengale, B. & Sarnes, M. Arch. Intern. Med. 163, 487–494 (2003).

    Article  PubMed  Google Scholar 

  2. Zhu, L. et al. Nat. Microbiol. 1, 16150 (2016).

    Article  CAS  PubMed  Google Scholar 

  3. Rossmann, M. G. et al. Nature 317, 145–153 (1985).

    Article  CAS  PubMed  Google Scholar 

  4. Hogle, J. M., Chow, M. & Filman, D. J. Science 27, 1358–1365 (1985).

    Article  Google Scholar 

  5. Zhu, L. et al. Nat. Commun. 6, 8316 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Wang, X. et al. Nature 517, 85–88 (2015).

    Article  CAS  PubMed  Google Scholar 

  7. Ren, J. et al. J. Virol. 89, 10500–10511 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Shakeel, S. et al. J. Virol. 89, 9571–9580 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Ren, J. et al. Nat. Commun. 4, 1929 (2013).

    Article  PubMed  PubMed Central  Google Scholar 

  10. Pickl-Herk, A. et al. Proc. Natl Acad. Sci. USA 110, 20063–20068 (2013).

    Article  CAS  PubMed  Google Scholar 

  11. Strauss, M. et al. J. Virol. 89, 4143–4157 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Lee, H. et al. Sci. Adv. 2, e1501929 (2016).

    Article  PubMed  PubMed Central  Google Scholar 

  13. Kotecha, A. et al. Nat. Struct. Mol. Biol. 22, 788–794 (2015).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Chebrek, R., Leonard, S., de Brevern, A. G. & Gelly, J.-C. Database (Oxford) 2014, bau102 (2014).

    Article  Google Scholar 

  15. Adzhubei, A. A., Sternberg, M. J. & Makarov, A. A. J. Mol. Biol. 425, 2100–2132 (2013).

    Article  CAS  PubMed  Google Scholar 

Download references

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Correspondence to Susan Hafenstein.

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Hafenstein, S. Structural biology: A picornavirus unlike the others. Nat Microbiol 1, 16217 (2016). https://doi.org/10.1038/nmicrobiol.2016.217

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