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Archaeal physiology: The secrets of termination

Regulation of transcriptional termination in archaea has remained a mystery. Now, a high-throughput RNA sequencing approach identifies multiple archaeal genes that contain consecutive terminators, suggesting new ways by which these microorganisms regulate transcription.

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Figure 1: A schematic view of the archaeal RNAP structure showing the positions of the stalk structure carrying Rpo4/7, the DNA channel and the RNAP clamp.

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Correspondence to Roger A. Garrett.

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Garrett, R. Archaeal physiology: The secrets of termination. Nat Microbiol 1, 16159 (2016). https://doi.org/10.1038/nmicrobiol.2016.159

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