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Parasite pathogenesis: Breaching the wall for brain access

Parasite access to the central nervous system is a severe complication of infection. Toxoplasma gondii can achieve this by directly infecting, replicating in and lysing blood–brain barrier endothelial cells.

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Figure 1: Toxoplasma gondii entry into the CNS.


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Correspondence to Aarti Krishnan.

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Krishnan, A., Soldati-Favre, D. Parasite pathogenesis: Breaching the wall for brain access. Nat Microbiol 1, 16014 (2016).

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