Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Microbiome: Ecology of eczema

Nature Microbiology volume 1, Article number: 16135 (2016) Cite this article

Subjects

Patients with atopic dermatitis have fundamentally different skin microbial populations compared with people with healthy skin. Bacteria associated with atopic dermatitis express genes for survival in dry conditions and for ammonia production, modulating the pH of this distinct environment and driving complex ecological interactions.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: A comparison between the microbiomes of healthy patients and those who have atopic dermatitis.

References

  1. Leyden, J. J., Marples, R. R. & Kligman, A. M. Br. J. Dermatol. 90, 525–530 (1974).

    Article  CAS  Google Scholar 

  2. Oh, J. et al. Cell 165, 854–866 (2016).

    Article  CAS  Google Scholar 

  3. Grice, E. A. et al. Science 324, 1190–1192 (2009).

    Article  CAS  Google Scholar 

  4. Chng, K. R. et al. Nature Microbiol. 1, 16106 (2016).

    Article  CAS  Google Scholar 

  5. Saeki, H. et al. J. Dermatol. 33, 817–819 (2006).

    Article  Google Scholar 

  6. Asher, M. I. et al. Eur. Respir. J. 8, 483–491 (1995).

    Article  CAS  Google Scholar 

  7. Kong, H. H. et al. Genome Res. 22, 850–859 (2012).

    Article  CAS  Google Scholar 

  8. Cogen, A. L. et al. J. Invest. Dermatol. 130, 192–200 (2010).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Ian D. Odell is in the Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA.,

    Ian D. Odell

  2. Richard A. Flavell is in the Department of Immunobiology, School of Medicine, Yale University, New Haven, Connecticut 06520, USA.,

    Richard A. Flavell

Authors
  1. Ian D. Odell
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Richard A. Flavell
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Ian D. Odell or Richard A. Flavell.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Odell, I., Flavell, R. Microbiome: Ecology of eczema. Nat Microbiol 1, 16135 (2016). https://doi.org/10.1038/nmicrobiol.2016.135

Download citation

  • Published:

  • DOI: https://doi.org/10.1038/nmicrobiol.2016.135

This article is cited by

Search

Advanced search

Quick links

Nature Briefing Microbiology

Sign up for the Nature Briefing: Microbiology newsletter — what matters in microbiology research, free to your inbox weekly.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing: Microbiology