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Goodbye to brute force in antibiotic discovery?

Widespread antibiotic resistance is a growing public health problem. Can we revive large-scale screening to keep the pipelines flowing or will we depend increasingly on biological and ecological insights?

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Correspondence to Roberto Kolter or Gilles P. van Wezel.

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Kolter, R., van Wezel, G. Goodbye to brute force in antibiotic discovery?. Nat Microbiol 1, 15020 (2016).

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