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Multiple displacement amplification compromises quantitative analysis of metagenomes

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Figure 1: Correlations between OTU skewing and estimated genomic G+C content for the three environmental samples and three MDA protocols tested.


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We thank R. Scheffrahn and D. Jacobson for providing samples of worker termites and garden compost, respectively. This work was supported by the US Department of Energy, Office of Science, Office of Biological and Environmental Research, through contract DE-AC02-05CH11231 between Lawrence Berkeley National Laboratory and the US Department of Energy.

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Correspondence to Philip Hugenholtz.

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Yilmaz, S., Allgaier, M. & Hugenholtz, P. Multiple displacement amplification compromises quantitative analysis of metagenomes. Nat Methods 7, 943–944 (2010).

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