A novel atomic force microscopy (AFM) setup allows researchers to image and manipulate unsupported membrane proteins separating two aqueous compartments. This promises to permit new detailed measurements of protein conformational changes and interactions under native-like conditions.
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Dufrêne, Y. Atomic force microscopy of membrane proteins separating two aqueous compartments. Nat Methods 3, 973–975 (2006). https://doi.org/10.1038/nmeth1206-973
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DOI: https://doi.org/10.1038/nmeth1206-973
