Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

A database of mass spectrometric assays for the yeast proteome

Nature Methods volume 5, pages 913–914 (2008)Cite this article

To the editor:

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Learn more

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Categorization of the yeast proteins represented in MRMAtlas by function and cellular abundance.

References

  1. Domon, B. & Aebersold, R. Science 312, 212–217 (2006).

    Article  CAS  Google Scholar 

  2. Picotti, P., Aebersold, R. & Domon, B. Mol. Cell. Proteomics 6, 1589–1598 (2007).

    Article  CAS  Google Scholar 

  3. Kuster, B., Schirle, M., Mallick, P. & Aebersold, R. Nat. Rev. Mol. Cell Biol. 6, 577–583 (2005).

    Article  CAS  Google Scholar 

  4. Stahl-Zeng, J. et al. Mol. Cell. Proteomics 6, 1809–1817 (2007).

    Article  CAS  Google Scholar 

  5. Ghaemmaghami, S. et al. Nature 425, 737–741 (2003).

    Article  CAS  Google Scholar 

  6. Deutsch, E.W., Lam, H. & Aebersold, R. EMBO Rep. 9, 429–434 (2008).

    Article  CAS  Google Scholar 

Download references

Acknowledgements

We acknowledge C.H. Wong, V. Lange and L. Reiter for valuable assistance and insightful discussions; C. Miller and K. Miller, and N. Selevsek for testing the SRM assays developed in this study on Agilent and Thermo Fischer Scientific QQQ mass spectrometers, respectively; and R. Costenoble for valuable input and suggestions. This project was funded in part by the Swiss Federal Institute of Technology Zuerich, the Swiss National Science Foundation, with funds from the US National Heart, Lung, and Blood Institute, National Institutes of Health (N01-HV-28179) and by SystemsX.ch, the Swiss Initiative in Systems Biology. P.P. is the recipient of a Marie Curie Intra-European fellowship.

Author information

Author notes

  1. Henry Lam

    Present address: Present address: Department of Chemical and Biomolecular Engineering, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.,

  2. Paola Picotti, Henry Lam and David Campbell: These authors contributed equally to this work.

Authors and Affiliations

  1. Institute of Molecular Systems Biology, Swiss Federal Institute of Technology, Eidgenössische Technische Hochschule Zuerich, Wolfgang Pauli Str. 16, Zuerich, CH-8093, Switzerland

    Paola Picotti, Bruno Domon & Ruedi Aebersold

  2. Institute of Systems Biology, 1441 North 34th Street, Seattle, 98103, Washington, USA

    Henry Lam, David Campbell, Eric W Deutsch, Hamid Mirzaei, Jeff Ranish & Ruedi Aebersold

  3. Faculty of Science, University of Zuerich, Winterthurerstr. 190, Zuerich, CH-8057, Switzerland

    Ruedi Aebersold

  4. Competence Center for Systems Physiology and Metabolic Diseases, Schafmattstr. 18, Zuerich, CH-8093, Switzerland

    Ruedi Aebersold

Authors
  1. Paola Picotti
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Henry Lam
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. David Campbell
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Eric W Deutsch
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Hamid Mirzaei
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Jeff Ranish
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Bruno Domon
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Ruedi Aebersold
    View author publications

    You can also search for this author in PubMed Google Scholar

Supplementary information

Supplementary Text and Figures

Supplementary Methods, Supplementary Discussion, Supplementary Note (PDF 1327 kb)

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Picotti, P., Lam, H., Campbell, D. et al. A database of mass spectrometric assays for the yeast proteome. Nat Methods 5, 913–914 (2008). https://doi.org/10.1038/nmeth1108-913

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmeth1108-913

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing