Methods relying on dense arrays of synthetic oligodeoxynucleotides to target specific subsets of the human genome may enable routine resequencing of all human exons or multi-megabase-pair chromosomal regions.
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Olson, M. Enrichment of super-sized resequencing targets from the human genome. Nat Methods 4, 891–892 (2007). https://doi.org/10.1038/nmeth1107-891
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DOI: https://doi.org/10.1038/nmeth1107-891