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Antibody 'sandwich' serves up phosphorylation data


Initial tests of a new antibody-based microarray strategy demonstrate the potential for the rapid analysis of protein modification states in a variety of biological samples.

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Figure 1: A schematic of the Tempst group's 'micro-sandwich' strategy.


  1. Gembitsky, D.S. et al. A prototype antibody micro-array platform to monitor changes in protein tyrosine phosphorylation. Mol. Cell. Proteomics, published online 8 September 2004.

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Eisenstein, M. Antibody 'sandwich' serves up phosphorylation data. Nat Methods 1, 98–99 (2004).

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