Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

The age of high-throughput microRNA profiling

New advancements in microarray technology offer a stepping-stone to the biological function of microRNAs.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Figure 1: The RAKE assay offers a more efficient method to study the expression profiles of miRNAs using microarrays.


  1. Bartel, D.P. Cell 116, 281–97 (2004).

    CAS  Article  Google Scholar 

  2. Thomson, J.M., Parker, J., Perou, C.M. & Hammond, S.M. Nat. Methods 1, 47–53 (2004).

    CAS  Article  Google Scholar 

  3. Nelson, P.T. et al. Nat. Methods 1, 155–161 (2004).

    CAS  Article  Google Scholar 

  4. Calin, G.A. et al. Proc. Natl. Acad. Sci. USA 101, 2999–3004 (2004).

    CAS  Article  Google Scholar 

  5. McManus, M.T. Semin. Cancer Biol. 13, 253–258 (2003).

    CAS  Article  Google Scholar 

  6. Liu, C.G. et al. Proc. Natl. Acad. Sci. USA 101, 9740–9744 (2004).

    CAS  Article  Google Scholar 

  7. Miska, E.A. et al. Genome Biol. 5, R68 (2004).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations


Rights and permissions

Reprints and Permissions

About this article

Cite this article

Esquela-Kerscher, A., Slack, F. The age of high-throughput microRNA profiling. Nat Methods 1, 106–107 (2004).

Download citation

  • Issue Date:

  • DOI:

Further reading


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing