A combination of automated screening and next-generation sequencing makes it possible to identify Caenorhabditis elegans mutants at unprecedented speed and scale.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
XGAP: a uniform and extensible data model and software platform for genotype and phenotype experiments
Genome Biology Open Access 09 March 2010
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Doitsidou, M., Flames, N., Lee, A.C., Boyanov, A. & Hobert, O. Nat. Methods 5, 869–872 (2008).
Sarin, S., Prabhu, S., O'Meara, M.M., Pe'er, I. & Hobert, O. Nat. Methods 5, 865–867 (2008).
Pulak, R. Methods Mol. Biol. 351, 275–286 (2006).
Nass, R. et al. J. Neurochem. 94, 774–785 (2005).
Nass, R., Hall, D.H., Milerr, D.M., III & Balekely, R.D. Proc. Natl. Acad. Sci. USA 99, 3264–3269 (2002).
Sarin, S. et al. Genetics 176, 2109–2130 (2007).
Davis, M.W. et al. BMC Genomics 6, 118 (2005).
Anderson, P. Methods Cell Biol. 48 31–58 (1995).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Fay, D. Classical genetics goes high-tech. Nat Methods 5, 863–864 (2008). https://doi.org/10.1038/nmeth1008-863
Issue Date:
DOI: https://doi.org/10.1038/nmeth1008-863