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Hold me tightly LOV

Mutations that increase the dynamic range of a photoswitchable protein may be used to improve other such photoswitches and increase their potential for allosteric control of protein activity in live cells.

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Figure 1: LOV domain–based photoswitches.


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Correspondence to Klaus M Hahn or Brian Kuhlman.

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The authors declare no competing financial interests.

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Hahn, K., Kuhlman, B. Hold me tightly LOV. Nat Methods 7, 595–596 (2010).

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