Recently discovered electrophilic probes open the door to activity-based protein profiling (ABPP) studies of a broader range of proteins.
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References
Weerapana, E. et al. Disparate proteome reactivity profiles of carbon electrophiles. Nat. Chem. Biol., published online 18 May 2008.
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Pflumm, M. New electrophilic probes slide in. Nat Methods 5, 580–581 (2008). https://doi.org/10.1038/nmeth0708-580b
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DOI: https://doi.org/10.1038/nmeth0708-580b