Correspondence | Published:

Unexpected failure rates for modular assembly of engineered zinc fingers

Nature Methods volume 5, pages 374375 (2008) | Download Citation


  • An Erratum to this article was published on 01 June 2008

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Change history

  • 29 May 2008

    In the version of this correspondence initially published, the two previously published datasets analyzed were labeled with incorrect references in Figure 1b. Reference 2 should be associated with the second column (80 sites) and Reference 3 should be associated with the third column (96 sites).  The weblink for the Zinc Finger Consortium website was incorrect and should be  The errors have been corrected in the HTML and PDF versions of the article.


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We thank D. Dobbs and P. Zaback for helpful discussions and E. Unger-Wallace (Iowa State University) for contributions to zinc-finger array construction. J.K.J. is supported by the US National Institutes of Health (R21 RR024189), the Cystic Fibrosis Foundation (MCCRAY07G0) and the Massachusetts General Hospital Department of Pathology; D.F.V. is supported by a US National Science Foundation grant DBI 0501678; T.C. is supported by the German Research Foundation (SPP1230 CA311/2); C.L.R. is supported by a Ford Foundation Pre-Doctoral Diversity Fellowship and a National Science Foundation Graduate Research Fellowship; T.I.C. is supported by a fellowship from the Swiss Foundation for Grants in Biology and Medicine.

Author information

Author notes

    • Cherie L Ramirez
    •  & Jonathan E Foley

    These authors contributed equally to this work.


  1. Molecular Pathology Unit, Center for Cancer Research, and Center for Computational and Integrative Biology, 149 13th Street, Room 7132, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA.

    • Cherie L Ramirez
    • , Jonathan E Foley
    •  & J Keith Joung
  2. Biological and Biomedical Sciences Program, Division of Medical Sciences, Harvard Medical School, Boston, Massachusetts 02115, USA.

    • Cherie L Ramirez
    •  & J Keith Joung
  3. Department of Genetics, Development and Cell Biology, Iowa State University, 1035A Roy J. Carver Co-Lab, Ames, Iowa 50011, USA.

    • David A Wright
    • , Ronnie J Winfrey
    • , Jeffry D Sander
    • , Fengli Fu
    • , Jeffrey A Townsend
    •  & Daniel F Voytas
  4. Charité Medical School, Institute of Virology, Hindenburgdamm 27, D-12203 Berlin, Germany.

    • Felix Müller-Lerch
    • , Shamim H Rahman
    • , Tatjana I Cornu
    •  & Toni Cathomen
  5. Interdepartmental Graduate Program in Bioinformatics and Computational Biology, 2114 Molecular Biology Building, Iowa State University, Ames, Iowa 50011, USA.

    • Jeffry D Sander
    •  & Fengli Fu
  6. Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA.

    • J Keith Joung


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Corresponding author

Correspondence to J Keith Joung.

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