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The rise of the 'projectome'

A Corrigendum to this article was published on 01 July 2007

Although new super-resolution imaging techniques provide valuable biological insights, some applications, such as determining the organization of neural projections in the brain, are better served by comprehensive imaging of very large samples at lower resolution.

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Figure 1: A comparison of imaging methods based on their resolving ability and the magnitude of the resulting data set created from imaging a cubic millimeter sample of mouse brain, indicated by the box in the image.


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Kasthuri, N., Lichtman, J. The rise of the 'projectome'. Nat Methods 4, 307–308 (2007).

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