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Putting long-range mapping in reach

Nature Methods volume 3, page 239 (2006) | Download Citation



A technique for performing PCR on extremely large DNA molecules offers researchers the ability to generate accurate multi-marker haplotypes for large numbers of patients—even with loci arrayed across entire human chromosomes.

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    et al. Long-range polony haplotyping of individual human chromosome molecules. Nat. Genet. 38, 382–387 (2006).

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    & In situ localized amplification and contact replication of many individual DNA molecules. Nucleic Acids Res. 27, e34 (1999).

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