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Systematic variation improves reproducibility of animal experiments

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Figure 1: Effect of standardization and heterogenization on between-experiment variation.
Figure 2: Heterogenization improves reproducibility by increasing within-experiment variation as shown in the path length in a free exploration test.


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This study was supported by the German Research Foundation (Deutsche Forschungsgemeinschaft).

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Correspondence to Hanno Würbel.

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Richter, S., Garner, J., Auer, C. et al. Systematic variation improves reproducibility of animal experiments. Nat Methods 7, 167–168 (2010).

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