Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Software opens the door to quantitative imaging

Cellular imaging by fluorescence microscopy is becoming simultaneously higher-throughput and more quantitative as researchers develop integrated systems for image acquisition and analysis.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Microscope-based cytometry.

Katie Ris


  1. Gordon, A. et al. Nat. Methods 4, 175–181 (2007).

    Article  CAS  Google Scholar 

  2. Colman-Lerner, A. et al. Nature 437, 699–706 (2005).

    Article  CAS  Google Scholar 

  3. Mettetal, J.T., Muzzey, D., Pedraza, J.M., Ozbudak, E.M. & van Oudenaarden, A. Proc. Natl. Acad. Sci. USA 103, 7304–7309 (2006).

    Article  CAS  Google Scholar 

  4. Pedraza, J.M. & van Oudenaarden, A. Science 307, 1965–1969 (2005).

    Article  CAS  Google Scholar 

  5. Rosenfeld, N., Perkins, T.J., Alon, U., Elowitz, M.B. & Swain, P.S. Biophys. J. 91, 759–766 (2006).

    Article  CAS  Google Scholar 

  6. Rosenfeld, N., Young, J.W., Alon, U., Swain, P.S. & Elowitz, M.B. Science 307, 1962–1965 (2005).

    Article  CAS  Google Scholar 

  7. Wheeler, D.B. et al. Nat. Methods 1, 127–132 (2004).

    Article  CAS  Google Scholar 

  8. Conrad, C. et al. Genome Res. 14, 1130–1136 (2004).

    Article  CAS  Google Scholar 

  9. Neumann, B. et al. Nat. Methods 3, 385–390 (2006).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations


Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Carpenter, A. Software opens the door to quantitative imaging. Nat Methods 4, 120–121 (2007).

Download citation

  • Issue Date:

  • DOI:

This article is cited by


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing