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Tinkering with the fly genome

Nature Methods volume 4, page 114 (2007) | Download Citation



A new strategy provides a leap forward in making transgenic flies.

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    , et al. Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31. Genetics 166, 1775–1782 (2004).

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    et al. P[acman]: a BAC transgenic platform for targeted insertion of large DNA fragments in D. melanogaster. Science 314, 1747–1751 (2006).

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    et al. Conditionally amplifiable BACs: Switching from single-copy to high-copy vectors and genomic clones. Genome Res. 12, 1434–1444 (2002).

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