Intracellular protein-protein interactions form the basis of most biological processes. Structural aspects of these reactions can now be analyzed in living prokaryotic cells and in atomic detail by nuclear magnetic resonance spectroscopy.
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Selenko, P., Wagner, G. NMR mapping of protein interactions in living cells. Nat Methods 3, 80–81 (2006). https://doi.org/10.1038/nmeth0206-80
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DOI: https://doi.org/10.1038/nmeth0206-80