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Nature Methods volume 7, page 12 (2010) | Download Citation

Screening reveals a chemical activator that triggers apoptosis by locking inactive but dynamic proenzymes into a more active state, suggesting a promising strategy for targeting proteases.

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References

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    et al. Small-molecule activators of a proenzyme. Science 326, 853–858 (2009).

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Published

DOI

https://doi.org/10.1038/nmeth0110-12

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  1. Search for Michael Eisenstein in:

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