Supplementary Figure 4: Comparison of trendsceek mark-segregation summary statistics. | Nature Methods

Supplementary Figure 4: Comparison of trendsceek mark-segregation summary statistics.

From: Identification of spatial expression trends in single-cell gene expression data

Supplementary Figure 4

(A-D) Venn diagrams comparing significant genes identified with different trendsceek summary statistics for four different data sets; spatial transcriptomics mouse olfactory bulb, tissue section “replicate 3” (n=269 array-spots) (A), tissue section “replicate 12” (n=280 array-spots) (B), spatial transcriptomics breast cancer (n=251 array-spots) (C), and mouse gastrulation single-cell data (n=481 cells) (D). (E-H) Pair-wise comparison of summary statistics for 500 most variable genes for the four different data sets (same order and sample sizes as for A-D). Blue indicates smoothed gene density histogram. Numbers in lower left triangle of the matrices indicate Pearson correlation between each pair of summary statistics.

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