Supplementary Figure 8 : Targeting range of dCpf1-based activators.

From: Inducible and multiplex gene regulation using CRISPR–Cpf1-based transcription factors

Supplementary Figure 8

Graphs representing the percentage of NGG “desert” regions for 32,696 human TSSs that are targetable by (a) wild-type Cpf1 (TTTV PAM) and (b) wild-type Cpf1 together with two engineered Cpf1 variants (that recognize TYCV and TATV PAMs). TSSs were binned by the their total desert region lengths (in bps) and box plots of percentage coverage were generated for each bin.