Supplementary Figure 9: A comparison of the transcriptomes of expanded hiPSC-derived FD-SFTPC+ cells with those of human adult AT2 cells. | Nature Methods

Supplementary Figure 9: A comparison of the transcriptomes of expanded hiPSC-derived FD-SFTPC+ cells with those of human adult AT2 cells.

From: Long-term expansion of alveolar stem cells derived from human iPS cells in organoids

Supplementary Figure 9

(a) A Venn diagram showing 6142 adult AT2-specific genes listed by analyzing the transcriptomes of three conditions: primary adult AT2 cells isolated from human lung (n = 3 donors); P0, P2 and P5 hiPSC-derived FD-SFTPC+ cells (n = 3 independent experiments, each); CPMhi progenitor cells (n=3 biological replicates) (>2-fold upregulated genes, P < 0.05, ANOVA corrected by Benjamini-Hochberg FDR with Tukey’s post hoc). See also Supplementary Table 4. (b) A list of top 20 GO terms that were significantly annotated with adult AT2 specific genes (P < 0.05, Fisher’s exact test). See also Supplementary Table 5.

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