Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Research Highlights
  • Published:

Synthetic biology

Synthetic epigenetic memory

Combining an inducible methyltransferase with a methylation-sensitive zinc finger creates an epigenetic memory circuit.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

References

  1. Maier, J.A.H. et al. Design of synthetic epigenetic circuits featuring memory effects and reversible switiching based on DNA methylation. Nat. Commun. 8, 15336 (2017).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Authors

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Rusk, N. Synthetic epigenetic memory. Nat Methods 14, 764 (2017). https://doi.org/10.1038/nmeth.4382

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmeth.4382

Search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research