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A glance at N6-methyladenosine in transcript isoforms

Nature Methods volume 13, pages 624625 (2016) | Download Citation

A sequencing approach, m6A-LAIC-seq, globally quantifies the proportion of m6A-modified transcripts of a specific gene and the differential m6A modification levels among its isoforms.

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Author information

Affiliations

  1. Hailing Shi is at the Department of Chemistry, The University of Chicago, Chicago, Illinois, USA.

    • Hailing Shi
  2. Chuan He is at the Department of Chemistry, the Department of Biochemistry and Molecular Biology, the Institute for Biophysical Dynamics, and the Howard Hughes Medical Institute, The University of Chicago, Chicago, Illinois, USA.

    • Chuan He

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Chuan He.

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DOI

https://doi.org/10.1038/nmeth.3928

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