Supplementary Figure 5: Plating density affects division rate and drug sensitivity. | Nature Methods

Supplementary Figure 5: Plating density affects division rate and drug sensitivity.

From: Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs

Supplementary Figure 5

Spearman’s correlation between IC50 (top left), Emax (top right), GR50 (bottom left), or GRmax (bottom right) and number of divisions for six breast cancer cell lines. Data derive from an experiment in which cells were plated at a range of six densities and treated with eleven drugs having diverse mechanisms of action (see Online Methods and Supplementary Data 2). Significance: * for p<0.05, ** for p<0.01, and *** for p<0.001.

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