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Genomics

Cas9 and the importance of asymmetry

Nature Methods volume 13, pages 286287 (2016) | Download Citation

Short single-stranded DNA donors that asymmetrically span the Cas9 cut site show high efficiency in homology-directed editing.

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References

  1. 1.

    et al. Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA. Nat. Biotechnol. 34, 339–344 (2016).

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DOI

https://doi.org/10.1038/nmeth.3826

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  1. Search for Nicole Rusk in:

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