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Solutions for quantifying P-value uncertainty and replication power

Nature Methods volume 13, pages 107108 (2016) | Download Citation

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  1. 1.

    , , & Nat. Methods 12, 179–185 (2015).

  2. 2.

    Stat. Med. 11, 875–879 (1992).

  3. 3.

    Perspect. Psychol. Sci. 3, 286–300 (2008).

  4. 4.

    & Am. Stat. 65, 213–221 (2011).

  5. 5.

    , & Mol. Psychiatry 19, 1336–1340 (2014).

  6. 6.

    Nature 506, 150–152 (2014).

Download references


We thank the reviewers for their helpful comments and suggestions. This work was supported by the US National Institutes of Health (grant MH086135 to L.C.L. as part of the Consortium on the Genetics of Schizophrenia (COGS)) and the Cooperative Studies Program of the US Department of Veterans Affairs.

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  1. Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.

    • Laura C Lazzeroni
  2. Cooperative Studies Program Palo Alto Coordinating Center, Department of Veterans Affairs, Mountain View, California, USA.

    • Ying Lu
    •  & Ilana Belitskaya-Lévy
  3. Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California, USA.

    • Ying Lu


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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Laura C Lazzeroni.

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    Supplementary Software

    Statistical Intervals for P-value Evidence and Power (version 2.0).

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