Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Illuminating translation with ribosome profiling spectra

Software based on the spectral analysis of ribosome profiling improves the detection of translated segments in RNA molecules.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Spectral analysis of the triplet periodicity of ribosome profiles.

References

  1. Ingolia, N.T., Ghaemmaghami, S., Newman, J.R. & Weissman, J.S. Science 324, 218–223 (2009).

    Article  CAS  Google Scholar 

  2. Calviello, L. et al. Nat. Methods 13, 165–170 (2016).

    Article  CAS  Google Scholar 

  3. Michel, A.M. et al. Genome Res. 22, 2219–2229 (2012).

    Article  CAS  Google Scholar 

  4. Aspden, J.L. et al. Elife 3, e03528 (2014).

    Article  Google Scholar 

  5. Duncan, C.D. & Mata, J. Nat. Struct. Mol. Biol. 21, 641–647 (2014).

    Article  CAS  Google Scholar 

  6. Bazzini, A.A. et al. EMBO J. 33, 981–993 (2014).

    Article  CAS  Google Scholar 

  7. Thomson, D.J. Proc. IEEE 70, 1055–1096 (1982).

    Article  Google Scholar 

  8. Andreev, D.E. et al. Genome Biol. 16, 90 (2015).

    Article  Google Scholar 

  9. Ingolia, N.T. et al. Cell Rep. 8, 1365–1379 (2014).

    Article  CAS  Google Scholar 

  10. Fields, A.P. et al. Mol. Cell 60, 816–827 (2015).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Pavel V Baranov.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Baranov, P., Michel, A. Illuminating translation with ribosome profiling spectra. Nat Methods 13, 123–124 (2016). https://doi.org/10.1038/nmeth.3738

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmeth.3738

This article is cited by

Search

Quick links

Nature Briefing AI and Robotics

Sign up for the Nature Briefing: AI and Robotics newsletter — what matters in AI and robotics research, free to your inbox weekly.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing: AI and Robotics