Single-particle cryo-electron microscopy

A brief overview of how to solve a macromolecular structure using single-particle cryo-electron microscopy (cryo-EM).

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We thank R. Glaeser for his help in preparing this Primer.

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Doerr, A. Single-particle cryo-electron microscopy. Nat Methods 13, 23 (2016) doi:10.1038/nmeth.3700

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