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Pump up the volume

Nature Methods volume 12, pages 19–22 (2015)Cite this article

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Light-sheet fluorescence microscopy techniques are enabling researchers to achieve dynamic, long-term imaging and three-dimensional reconstruction of specimens ranging from single cells to whole embryos.

Consider two microscopes. The first images entire embryos or living organs with astonishing speed and resolution. Using this instrument, Jan Huisken's team at the Max Planck Institute for Heart and Lung Research could reconstruct a beating zebrafish heart, with a rapidity and precision that even captured red blood cells careening through its chambers (Nat. Methods 11, 919–922, 2014).

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  1. Michael Eisenstein
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Eisenstein, M. Pump up the volume. Nat Methods 12, 19–22 (2015). https://doi.org/10.1038/nmeth.3220

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  • DOI: https://doi.org/10.1038/nmeth.3220

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