Two high-throughput single-molecule force spectroscopy platforms expand the reach of this technology for biomechanical molecular phenotyping.
This is a preview of subscription content, access via your institution
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Rent or buy this article
Prices vary by article type
Prices may be subject to local taxes which are calculated during checkout
Otten, M. et al. Nat. Methods 11, 1127–1130 (2014).
Sitters, G. et al. Nat. Methods 12, 47–50 (2015).
Neuman, K.C. & Nagy, A. Nat. Methods 5, 491–505 (2008).
Müller, D.J. & Dufrene, Y.F. Nat. Nanotechnol. 3, 261–269 (2008).
Maerkl, S.J. & Quake, S.R. Science 315, 233–237 (2007).
Fordyce, P.M. et al. Nat. Biotechnol. 28, 970–975 (2010).
Struckmeier, J. et al. Nanotechnology 19, 384020 (2008).
Chiou, P.Y., Ohta, A.T. & Wu, M.C. Nature 436, 370–372 (2005).
De Vlaminck, I. et al. Nano Lett. 11, 5489–5493 (2011).
Otten, M., Wolf, P. & Gaub, H.E. Lab Chip 13, 4198–4204 (2013).
Streets, A.M. & Huang, Y. Curr. Opin. Biotechnol. 25, 69–77 (2014).
The authors declare no competing financial interests.
About this article
Cite this article
Alsteens, D., Tay, S. & Müller, D. Toward high-throughput biomechanical phenotyping of single molecules. Nat Methods 12, 45–46 (2015). https://doi.org/10.1038/nmeth.3216
This article is cited by
Nature Reviews Physics (2020)