A decade of advances in genome engineering technologies has enabled the editing of genome sequences much like one edits computer code; many more applications for precisely manipulating genome structure and function are on the horizon.
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Acknowledgements
I thank the members of the Gersbach laboratory and our collaborators that have contributed to our work in this area. C.A.G. is supported by US National Institutes of Health (NIH) Director's New Innovator Award (DP2OD008586), US National Science Foundation (NSF) Faculty Early Career Development (CAREER) Award (CBET-1151035), NIH R01DA036865, NIH R21AR065956 and the Muscular Dystrophy Association (MDA277360).
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C.A.G. is an inventor on patent applications related to genome engineering and a scientific advisor to Editas Medicine, a company engaged in therapeutic development of genome engineering tools.
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Gersbach, C. Genome engineering: the next genomic revolution. Nat Methods 11, 1009–1011 (2014). https://doi.org/10.1038/nmeth.3113
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DOI: https://doi.org/10.1038/nmeth.3113
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