CRISPR-based transcriptional activators and repressors for synthetic circuits.
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References
Kiani, S., et al. CRISPR transcriptional repression devices and layered circuits in mammalian cells. Nat. Methods 11, 723–726 (2014).
Nissim, L. et al. Multiplexed and programmable regulation of genetic networks with an integrated RNA and CRISPR/Cas toolkit in human cells. Mol. Cell 54, 698–710 (2014).
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Rusk, N. CRISPR circuits. Nat Methods 11, 710–711 (2014). https://doi.org/10.1038/nmeth.3019
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DOI: https://doi.org/10.1038/nmeth.3019