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Synthetic biology

CRISPR circuits

CRISPR-based transcriptional activators and repressors for synthetic circuits.

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References

  1. Kiani, S., et al. CRISPR transcriptional repression devices and layered circuits in mammalian cells. Nat. Methods 11, 723–726 (2014).

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  2. Nissim, L. et al. Multiplexed and programmable regulation of genetic networks with an integrated RNA and CRISPR/Cas toolkit in human cells. Mol. Cell 54, 698–710 (2014).

    Article  CAS  Google Scholar 

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Rusk, N. CRISPR circuits. Nat Methods 11, 710–711 (2014). https://doi.org/10.1038/nmeth.3019

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