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CPTAC Assay Portal: a repository of targeted proteomic assays

Nature Methods volume 11, pages 703–704 (2014)Cite this article

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To the Editor:

A growing trend in protein quantification is a targeted mass spectrometry (MS)-based technology called multiple reaction monitoring (MRM) or selected reaction monitoring (SRM). Here, we present the Clinical Proteomic Tumor Analysis Consortium (CPTAC) Assay Portal (http://assays.cancer.gov/), a public repository of well-characterized, MS-based, targeted proteomic assays.

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Figure 1: Overview of the CPTAC assay portal.

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Acknowledgements

This work was funded by the Clinical Proteomic Tumor Analysis Consortium (CPTAC) of the US National Cancer Institute under grant nos. U24CA160034 (S.A.C., A.G.P.), U24CA160036 (D.W.C.), U24CA160019 (R.D.S., K.D.R.), U24CA159988 (D.C.L.) and U24CA160035 (M.J.C.E.), as well as US National Institutes of Health grant nos. R01GM103551 (M.J.M.) and U01CA164186 (M.J.M.).

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Authors and Affiliations

  1. Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

    Jeffrey R Whiteaker, Ping Yan, Jacob Kennedy & Amanda G Paulovich

  2. Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, Maryland, USA

    Goran N Halusa, Michael Loss & Gordon Whiteley

  3. Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA

    Andrew N Hoofnagle

  4. Department of Genome Sciences, University of Washington, Seattle, Washington, USA

    Vagisha Sharma, Brendan MacLean & Michael J MacCoss

  5. Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA

    John A Wrobel & Xian Chen

  6. Broad Institute, Cambridge, Massachusetts, USA

    D R Mani, Susan E Abbatiello, Steven A Carr & Eric Kuhn

  7. Department of Biochemistry and Jim Ayers Institute for Precancer Detection and Diagnosis, Vanderbilt University School of Medicine, Nashville, Tennessee, USA

    Lisa J Zimmerman, Daniel C Liebler & De Lin

  8. Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA

    Matthew R Meyer, Sherri R Davies, Matthew J C Ellis & R Reid Townsend

  9. Office of Cancer Clinical Proteomics Research, National Cancer Institute, Bethesda, Maryland, USA

    Mehdi Mesri, Henry Rodriguez, Emily Boja, Tara Hiltke, Chris Kinsinger & Robert Rivers

  10. Department of Pathology, Clinical Chemistry Division, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

    Daniel W Chan, Jing Chen, Stefani Thomas, Hui Zhang & Zhen Zhang

  11. Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York, USA

    David Fenyö & Kelly V Ruggles

  12. Data Coordinating Center, ESAC, Inc., Rockville, Maryland, USA

    Karen A Ketchum

  13. Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USA

    Tao Liu, Wei-Jun Qian, Karin D Rodland, Richard D Smith & Chaochao Wu

  14. Department of Pathology and Immunology, Division of Laboratory and Genomic Medicine, Washington University School of Medicine, St. Louis, Missouri, USA

    Mitchell G Scott

Authors
  1. Jeffrey R Whiteaker
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  2. Goran N Halusa
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  4. Vagisha Sharma
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  5. Brendan MacLean
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  6. Ping Yan
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  7. John A Wrobel
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  8. Jacob Kennedy
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  9. D R Mani
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  10. Lisa J Zimmerman
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  11. Matthew R Meyer
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  13. Henry Rodriguez
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  14. Amanda G Paulovich
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Consortia

the Clinical Proteomic Tumor Analysis Consortium (CPTAC)

  • Susan E Abbatiello
  • , Emily Boja
  • , Steven A Carr
  • , Daniel W Chan
  • , Xian Chen
  • , Jing Chen
  • , Sherri R Davies
  • , Matthew J C Ellis
  • , David Fenyö
  • , Tara Hiltke
  • , Karen A Ketchum
  • , Chris Kinsinger
  • , Eric Kuhn
  • , Daniel C Liebler
  • , De Lin
  • , Tao Liu
  • , Michael Loss
  • , Michael J MacCoss
  • , Wei-Jun Qian
  • , Robert Rivers
  • , Karin D Rodland
  • , Kelly V Ruggles
  • , Mitchell G Scott
  • , Richard D Smith
  • , Stefani Thomas
  • , R Reid Townsend
  • , Gordon Whiteley
  • , Chaochao Wu
  • , Hui Zhang
  •  & Zhen Zhang

Corresponding author

Correspondence to Amanda G Paulovich.

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Competing interests

The authors declare no competing financial interests.

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Whiteaker, J., Halusa, G., Hoofnagle, A. et al. CPTAC Assay Portal: a repository of targeted proteomic assays. Nat Methods 11, 703–704 (2014). https://doi.org/10.1038/nmeth.3002

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