Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Correspondence
  • Published:

KinomeXplorer: an integrated platform for kinome biology studies

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Overview of the improved NetworKIN algorithm in KinomeXplorer.


  1. Seet, B.T., Dikic, I., Zhou, M.M. & Pawson, T. Nat. Rev. Mol. Cell Biol. 7, 473–483 (2006).

    Article  CAS  Google Scholar 

  2. Lim, W.A. & Pawson, T. Cell 142, 661–667 (2010).

    Article  CAS  Google Scholar 

  3. Davis, M.I. et al. Nat. Biotechnol. 29, 1046–1051 (2011).

    Article  CAS  Google Scholar 

  4. Anastassiadis, T., Deacon, S.W., Devarajan, K., Ma, H. & Peterson, J.R. Nat. Biotechnol. 29, 1039–1045 (2011).

    Article  CAS  Google Scholar 

  5. Dinkel, H. et al. Nucleic Acids Res. 39, D261–D267 (2011).

    Article  CAS  Google Scholar 

  6. Linding, R. et al. Cell 129, 1415–1426 (2007).

    Article  CAS  Google Scholar 

  7. Janes, K.A. et al. Science 310, 1646–1653 (2005).

    Article  CAS  Google Scholar 

  8. Yaffe, M.B. Sci. Signal. 6, pe13 (2013).

    PubMed  Google Scholar 

  9. Miller, M.L. et al. Sci. Signal. 1, ra2 (2008).

    Article  Google Scholar 

  10. Gough, N.R. Sci. Signal. 6, eg3 (2013).

    PubMed  Google Scholar 

Download references


We would like to thank members of R.L.'s laboratory for useful input on the manuscript, and A. Pasculescu for input on the data collection. This work was supported by the Lundbeck Foundation, the Human Frontier Science Program (HFSP), the Danish Council for Independent Research (FSS) and the European Research Council (ERC).

Author information

Authors and Affiliations


Corresponding authors

Correspondence to Lars Juhl Jensen or Rune Linding.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Supplementary information

Supplementary Text and Figures

Supplementary Figures 1 and 2, and Supplementary Note (PDF 757 kb)

Supplementary Table 1

Benchmark of the NetworKIN method (XLS 44 kb)

Supplementary Table 2

Dataset for training NetPhorest and NetworKIN (XLS 3640 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Horn, H., Schoof, E., Kim, J. et al. KinomeXplorer: an integrated platform for kinome biology studies. Nat Methods 11, 603–604 (2014).

Download citation

  • Published:

  • Issue Date:

  • DOI:

This article is cited by


Quick links

Nature Briefing AI and Robotics

Sign up for the Nature Briefing: AI and Robotics newsletter — what matters in AI and robotics research, free to your inbox weekly.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing: AI and Robotics