An approach is described that simplifies the isolation of rare human pluripotent stem cells engineered to carry precise disease-relevant mutations.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Urnov, F.D. et al. Nature 435, 646–651 (2005).
Miller, J.C. et al. Nat. Biotechnol. 29, 143–148 (2011).
Jinek, M. et al. Science 337, 816–821 (2012).
Hockemeyer, D. et al. Nat. Biotechnol. 27, 851–857 (2009).
Hockemeyer, D. et al. Nat. Biotechnol. 29, 731–734 (2011).
Mali, P. et al. Science 339, 823–826 (2013).
Soldner, F. et al. Cell 146, 318–331 (2011).
Miyaoka, Y. et al. Nat. Methods 11, 291–293 (2014).
Merkert, S. et al. Stem Cell Reports 2, 107–118 (2014).
Hou, Z. et al. Proc. Natl. Acad. Sci. USA 110, 15644–15649 (2013).
Esvelt, K.M. et al. Nat. Methods 10, 1116–1121 (2013).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Forster, R., Hockemeyer, D. Genome editing 101: let's go digital. Nat Methods 11, 248–249 (2014). https://doi.org/10.1038/nmeth.2859
Published:
Issue Date:
DOI: https://doi.org/10.1038/nmeth.2859