Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Genomics: the state of the art in RNA-seq analysis

RNA-seq is a recent and immensely popular technology for cataloging and comparing gene expression. Two papers from the international RGASP consortium report on large-scale competitions to identify the best algorithms for RNA-seq analysis, with surprising variability in the results.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Rent or buy this article

Prices vary by article type



Prices may be subject to local taxes which are calculated during checkout

Figure 1

Abigail Yu


  1. Steijger, T. et al. Nat. Methods 10, 1177–1184 (2013).

    Article  CAS  Google Scholar 

  2. Engström, P.G. et al. Nat. Methods 10, 1185–1191 (2013).

    Article  Google Scholar 

  3. Nakamura, K. et al. Nucleic Acids Res. 39, e90 (2011).

    Article  CAS  Google Scholar 

  4. Stanke, M. et al. Nucleic Acids Res. 34, W435–W439 (2006).

    Article  CAS  Google Scholar 

  5. Schweikert, G. et al. Genome Res. 19, 2133–2143 (2009).

    Article  CAS  Google Scholar 

  6. Bradnam, K.R. et al. GigaScience 2, 10 (2013).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Ian Korf.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Korf, I. Genomics: the state of the art in RNA-seq analysis. Nat Methods 10, 1165–1166 (2013).

Download citation

  • Published:

  • Issue Date:

  • DOI:

This article is cited by


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing