Exploring long-range genome interactions using the WashU Epigenome Browser

Article metrics

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Figure 1: Two genomic regions as viewed in the WashU Epigenome Browser.


  1. 1

    Dekker, J. Science 319, 1793–1794 (2008).

  2. 2

    Sanyal, A., Lajoie, B.R., Jain, G. & Dekker, J. Nature 489, 109–113 (2012).

  3. 3

    Lieberman-Aiden, E. et al. Science 326, 289–293 (2009).

  4. 4

    Handoko, L. et al. Nat. Genet. 43, 630–638 (2011).

  5. 5

    Dixon, J.R. et al. Nature 485, 376–380 (2012).

  6. 6

    Li, G. et al. Cell 148, 84–98 (2012).

  7. 7

    Lajoie, B.R., van Berkum, N.L., Sanyal, A. & Dekker, J. Nat. Methods 6, 690–691 (2009).

  8. 8

    Maunakea, A.K. et al. Nature 466, 253–257 (2010).

  9. 9

    Stamatoyannopoulos, J.A. Genome Res. 22, 1602–1611 (2012).

  10. 10

    Zhou, X. et al. Nat. Methods 8, 989–990 (2011).

Download references


We thank the laboratories of B. Ren, C.-L. Wei, Y. Ruan, J. Dekker; the UCSC Genome Browser team; and the ENCODE Consortium for providing long-range interaction data sets; and the Roadmap Epigenomics Consortium for providing epigenomics data sets. We thank many collaborators in the Roadmap Epigenomics Consortium who participated in software testing and provided helpful comments. We acknowledge support from the US National Institutes of Health (NIH) Roadmap Epigenomics Program, sponsored by the National Institute on Drug Abuse (NIDA) and the National Institute of Environmental Health Sciences (NIEHS). J.F.C. and T.W. are supported by NIH grant 5U01ES017154. X.Z. is supported by NIDA's R25 program DA027995. T.W. is supported in part by the March of Dimes Foundation, the Edward Jr. Mallinckrodt Foundation, NIH P50CA134254 and a grant from the Foundation for Barnes-Jewish Hospital.

Author information

Correspondence to Joseph F Costello or Ting Wang.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Supplementary information

Supplementary Text and Figures

Supplementary Figures 1–5, Supplementary Methods and Supplementary Notes 1 and 2 (PDF 4734 kb)

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Zhou, X., Lowdon, R., Li, D. et al. Exploring long-range genome interactions using the WashU Epigenome Browser. Nat Methods 10, 375–376 (2013) doi:10.1038/nmeth.2440

Download citation

Further reading