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Small RNAs

Leaner, meaner siRNAs

Nature Methods volume 9, page 1050 (2012) | Download Citation


Single-stranded small interfering RNA offers a potent and simple way to silence gene expression in the body.

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    et al. Single-stranded siRNAs activate RNAi in animals. Cell 150, 883–894 (2012).

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    et al. Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression. Cell 150, 895–908 (2012).

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