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CircadiOmics: integrating circadian genomics, transcriptomics, proteomics and metabolomics

Nature Methods volume 9, pages 772–773 (2012)Cite this article

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To the Editor:

Circadian rhythms govern a large array of physiological and metabolic functions1. It is critical to decode circadian oscillations by integrating multiple 'omic' approaches. Circadian genomic and transcriptomic data sets are accessible, and recently, metabolomics data in the circadian context also have been made available2. The components for building a comprehensive map of circadian networks are thus ready for assembly.

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Figure 1: Data integration workflow.

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Acknowledgements

We thank J. Hayes for helping with the development and deployment of the web server. This work was supported by US National Institutes of Health (NIH) National Research Service Award F32 DK083881 (to K.E.-M.), NIH GM081634 and AG033888 (to P.S.-C.), Sirtris Pharmaceuticals SP-48984 (to P.S.-C.), National Science Foundation IIS-0513376 (to P.B.), NIH LM010235 (to P.B.) and NIH National Library of Medicine T15 LM07443 (to P.B.).

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Authors and Affiliations

  1. Department of Computer Science, University of California, Irvine (UCI), Irvine, California, USA

    Vishal R Patel & Pierre Baldi

  2. Institute for Genomics and Bioinformatics, UCI, Irvine, California, USA

    Vishal R Patel, Paolo Sassone-Corsi & Pierre Baldi

  3. Department of Biological Chemistry, UCI, Irvine, California, USA

    Kristin Eckel-Mahan, Paolo Sassone-Corsi & Pierre Baldi

  4. Center for Epigenetics and Metabolism, UCI, Irvine, California, USA

    Kristin Eckel-Mahan, Paolo Sassone-Corsi & Pierre Baldi

Authors
  1. Vishal R Patel
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  2. Kristin Eckel-Mahan
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  3. Paolo Sassone-Corsi
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  4. Pierre Baldi
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Corresponding authors

Correspondence to Paolo Sassone-Corsi or Pierre Baldi.

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The authors declare no competing financial interests.

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Patel, V., Eckel-Mahan, K., Sassone-Corsi, P. et al. CircadiOmics: integrating circadian genomics, transcriptomics, proteomics and metabolomics. Nat Methods 9, 772–773 (2012). https://doi.org/10.1038/nmeth.2111

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