Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

'Self-healing' dyes: intramolecular stabilization of organic fluorophores

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Figure 1: Proposed model for photostabilization.


  1. 1

    Rasnik, I., McKinney, S.A. & Ha, T.J. Nat. Methods 3, 891–893 (2006).

    CAS  Article  Google Scholar 

  2. 2

    Vogelsang, J. et al. Angew. Chem. Int. Ed. 47, 5465–5468 (2008).

    CAS  Article  Google Scholar 

  3. 3

    Dave, R., Terry, D.S., Munro, J.B. & Blanchard, S.C. Biophys. J. 96, 2371–2381 (2009).

    CAS  Article  Google Scholar 

  4. 4

    Altman, R.B. et al. Nat. Methods 9, 68–71 (2012).

    CAS  Article  Google Scholar 

  5. 5

    Cordes, T., Vogelsang, J. & Tinnefeld, P. J. Am. Chem. Soc. 131, 5018–5019 (2009).

    CAS  Article  Google Scholar 

  6. 6

    Buettner, G.R. Arch. Biochem. Biophys. 300, 535–543 (1993).

    CAS  Article  Google Scholar 

Download references

Author information



Corresponding authors

Correspondence to Philip Tinnefeld or Thorben Cordes.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Tinnefeld, P., Cordes, T. 'Self-healing' dyes: intramolecular stabilization of organic fluorophores. Nat Methods 9, 426–427 (2012).

Download citation

Further reading


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing