Protein interaction data curation: the International Molecular Exchange (IMEx) consortium

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  • A Corrigendum to this article was published on 30 May 2012


The International Molecular Exchange (IMEx) consortium is an international collaboration between major public interaction data providers to share literature-curation efforts and make a nonredundant set of protein interactions available in a single search interface on a common website ( Common curation rules have been developed, and a central registry is used to manage the selection of articles to enter into the dataset. We discuss the advantages of such a service to the user, our quality-control measures and our data-distribution practices.

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Figure 1: Overview of the IMEx dataset.

Change history

  • 10 April 2012

    In the version of this article initially published, the names of two authors, Fiona S.L. Brinkman and Robert E.W. Hancock, were incorrectly listed without middle initials. The error has been corrected in the HTML and PDF versions of the article.


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This work was supported by the European Commission under PSIMEx, contract FP7-HEALTH-2007-223411, and in part by AntiPathoGN contract number HEALTH-F3-2009-223101, Serving Life-science Information for the Next Generation contract number 226073, Apoptosis Systems Biology Applied to Cancer and AIDS contract number FP7-HEALTH-2007-200767, the Ontario Research Fund (GL2-01-030), Canada Foundation for Innovation (CFI #12301 and CFI #203383), the Grand Challenges in Global Health program through the Foundation for the US National Institutes of Health and Canadian Institutes for Health Research, and Genome Canada and National Institutes of Health grant GM071909.

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Correspondence to Sandra Orchard.

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Competing interests

J.B., U.M. and A.R. are employees of Molecular Connections, a contract annotation company.

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