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Gene expression deconvolution in linear space

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Figure 1: Unbiased estimation of cell type–specific profiles.

References

  1. Shen-Orr, S.S. et al. Nat. Methods 7, 287–289 (2010).

    CAS  Article  Google Scholar 

  2. Quackenbush, J. Nat. Genet. 32, 496–501 (2002).

    CAS  Article  Google Scholar 

  3. Strang, G. Calculus 652 (Wellesley-Cambridge, 1991).

    Google Scholar 

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Acknowledgements

We thank H.Y. Zoghbi, J. Botas, L.A. Chodosh, J. Alvarez, O. Lichtarge and T. Klisch for helpful insights and critical comments on this manuscript.

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Correspondence to Zhandong Liu.

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Zhong, Y., Liu, Z. Gene expression deconvolution in linear space. Nat Methods 9, 8–9 (2012). https://doi.org/10.1038/nmeth.1830

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