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Tracking genomic hydroxymethylation by the base

Nature Methods volume 9, pages 45–46 (2012)Cite this article

An Erratum to this article was published on 29 April 2013

This article has been updated

A method uses single-molecule, real-time DNA sequencing to detect the modified base 5-hydroxymethylcytosine, an epigenetic mark recently suspected of having essential roles in genome regulation.

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Figure 1: 5-hmC detection by SMRT sequencing.

Change history

  • 18 February 2013

    In the version of this article initially published, ref. 1 contained an incorrect volume number and year. The errors have been corrected in the HTML and PDF versions of the article.

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Authors and Affiliations

  1. Gilles Salbert is at the Centre National de la Recherche Scientifique (CNRS) Unité Mixte de Recherche (UMR) 6026, Molecular and Cellular Interactions, University of Rennes 1, France.,

    Gilles Salbert

  2. Michael Weber is at the CNRS UMR 7242, Biotechnology and Cell Signalling, University of Strasbourg, Illkirch, France.,

    Michael Weber

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  1. Gilles Salbert
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  2. Michael Weber
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Correspondence to Gilles Salbert or Michael Weber.

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Salbert, G., Weber, M. Tracking genomic hydroxymethylation by the base. Nat Methods 9, 45–46 (2012). https://doi.org/10.1038/nmeth.1813

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