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SignalP 4.0: discriminating signal peptides from transmembrane regions

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Figure 1: Comparison of signal peptide prediction algorithm performance shown as the Matthews correlation coefficient for eukaryotes, Gram-positive bacteria and Gram-negative bacteria.


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Correspondence to Henrik Nielsen.

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Competing interests

The downloadable version of SignalP 4.0 (for local use) has been commercialized by the Technical University of Denmark. (It is provided for a fee to commercial users.) The revenue from these commercial sales is divided between the program developers (T.N.P., S.B., G.v.H. and H.N.) and the Technical University of Denmark, where T.N.P., S.B. and H.N. are employed.

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Petersen, T., Brunak, S., von Heijne, G. et al. SignalP 4.0: discriminating signal peptides from transmembrane regions. Nat Methods 8, 785–786 (2011).

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