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Matrix degradation

Making way for neural stemness

The influence of matrix stiffness and degradation on neural progenitor cell stemness was investigated in a three-dimensional culture system, highlighting the role of remodelling in enhancing cell-to-cell interaction and ultimately maintaining neural stemness.

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Figure 1: The role of matrix degradation in neural progenitor cell stemness.

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Correspondence to Sanjay Kumar or David V. Schaffer.

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Kang, P., Kumar, S. & Schaffer, D. Making way for neural stemness. Nature Mater 16, 1174–1176 (2017). https://doi.org/10.1038/nmat5043

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