News and Views

Cellular adhesion: Instant integrin mechanosensing

Single-cell force spectroscopy reveals rapid, biphasic integrin activation and reinforcement of cell–matrix bonds during the initial steps of fibroblast adhesion.

  • Subscribe to Nature Materials for full access:

    $59

    Subscribe

Additional access options:

Already a subscriber?  Log in  now or  Register  for online access.

References

  1. 1.

    et al. Cell 46, 271–82 (1986).

  2. 2.

    & Nature 309, 30–33 (1984).

  3. 3.

    , & Science 260, 1124–1127 (1993).

  4. 4.

    et al. Science 323, 638–641 (2009).

  5. 5.

    et al. Nature 466, 263–266 (2010).

  6. 6.

    , , , & Nat. Mater. 16, 1262–1270 (2017).

  7. 7.

    et al. Mol. Biol. Cell 18, 1634–1644 (2007).

  8. 8.

    et al. EMBO J. 27, 458–469 (2008).

  9. 9.

    , , , & J. Cell Biol. 185, 1275–1284 (2009).

  10. 10.

    et al. Proc. Natl Acad. Sci. USA 110, 19372–19377 (2013).

  11. 11.

    et al. Proc. Natl Acad. Sci. USA 105, 6626–6631 (2008).

  12. 12.

    et al. J. Cell Biol. 189, 1107–1115 (2010).

Download references

Author information

Affiliations

  1. Ning Wang is in the Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China, and the Department of Mechanical Science and Engineering, College of Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA

    • Ning Wang

Authors

  1. Search for Ning Wang in:

Corresponding author

Correspondence to Ning Wang.